Many sites now offer Multi-Hand Blackjack which is played with five standard decks of 52 playing cards that are shuffled before each game.
To win you must beat the Dealer's hand by either getting a beter hand, without going bust, or by the Dealer' going bust.
The key difference in this variant, is that you can only bet on multiple hands simultaneously. Generally the maximum number of hands that you can bet on is 5, but this depends on the online casino offering the blackjack variant.